263011926301221087382411389764GOCmccdef2828927OntologyLoader1.02017-03-09T16:31:20+01:00http://www.goontology.org/2017-03-09T16:30:51+01:00rootGO Ontolgy2017-03-09T00:00:00+01:00Inserted1.022The distribution of mitochondria, including the mitochondrial genome, into daughter cells after mitosis or meiosis, mediated by interactions between mitochondria and the cytoskeleton.GO:0000001falsemitochondrion inheritancebiological_process27202912603718exactmitochondrial inheritance272029127202912603718exact26037182609359GOCaidef2828262GOCvwdef2830609OntologyLoader1.02017-03-09T16:31:20+01:00http://www.goontology.org/2017-03-09T16:30:51+01:00rootGO Ontolgy2017-03-09T00:00:00+01:00Inserted1.022The maintenance of the structure and integrity of the mitochondrial genome; includes replication and segregation of the mitochondrial chromosome.GO:0000002falsemitochondrial genome maintenancebiological_process2603719GO:0019952GO:00508762610070goslim_chemblChEMBL protein targets su2603703goslim_plantPlant GO slim2603709goslim_pirPIR GO slim2603708gosubset_prokProkaryotic GO subset2603714goslim_genericGeneric GO slim2603704GOCjldef2828875GOCisa_completedef2828864ISBN0198506732def2774934WikipediaReproductionxref_analog2827468GOCgo_curatorsdef2828596OntologyLoader1.02017-03-09T16:31:20+01:00http://www.goontology.org/2017-03-09T16:30:51+01:00rootGO Ontolgy2017-03-09T00:00:00+01:00Inserted1.022The production of new individuals that contain some portion of genetic material inherited from one or more parent organisms.GO:0000003falsereproductionbiological_process27490272603720exactreproductive physiological process274902727490272603720exact260372012150913262448126262942631766GOCjldef2828875This term was made obsolete because it refers to a class of gene products and a biological process rather than a molecular function.OntologyLoader1.02017-03-09T16:31:20+01:00http://www.goontology.org/2017-03-09T16:30:51+01:00rootGO Ontolgy2017-03-09T00:00:00+01:00Inserted1.022OBSOLETE. Assists in the correct assembly of ribosomes or ribosomal subunits in vivo, but is not a component of the assembled ribosome when performing its normal biological function.GO:0000005trueobsolete ribosomal chaperone activitymolecular_function27500392603721exactribosomal chaperone activity275003927500392603721exact26037212607956TC2.A.5.1.1def2784757OntologyLoader1.02017-03-09T16:31:20+01:00http://www.goontology.org/2017-03-09T16:30:51+01:00rootGO Ontolgy2017-03-09T00:00:00+01:00Inserted1.022Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: Zn2+(out) = Zn2+(in), probably powered by proton motive force. In high-affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations.GO:0000006falsehigh-affinity zinc uptake transmembrane transporter activitymolecular_function27083672603722exacthigh affinity zinc uptake transmembrane transporter activity270836727083672603722exact26037222607956GOCmtg_transportdef2828983ISBN0815340729def2775103OntologyLoader1.02017-03-09T16:31:20+01:00http://www.goontology.org/2017-03-09T16:30:51+01:00rootGO Ontolgy2017-03-09T00:00:00+01:00Inserted1.022Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: Zn2+ = Zn2+, probably powered by proton motive force. In low-affinity transport the transporter is able to bind the solute only if it is present at very high concentrations.GO:0000007falselow-affinity zinc ion transmembrane transporter activitymolecular_function2603723GO:000001326065622613023GOCkddef2828884This term was made obsolete because it represents gene products.OntologyLoader1.02017-03-09T16:31:20+01:00http://www.goontology.org/2017-03-09T16:30:51+01:00rootGO Ontolgy2017-03-09T00:00:00+01:00Inserted1.022OBSOLETE. A small disulfide-containing redox protein that serves as a general protein disulfide oxidoreductase. Interacts with a broad range of proteins by a redox mechanism, based on the reversible oxidation of 2 cysteine thiol groups to a disulfide, accompanied by the transfer of 2 electrons and 2 protons. The net result is the covalent interconversion of a disulfide and a dithiol.GO:0000008trueobsolete thioredoxinmolecular_function27551872603724exactthioredoxin275518727551872603724exact260372426037432644248ReactomeREACT_22383Addition of a third mannose to the N-glycan precursor by ALG2, Homo sapiensxref_analog2808430GOCmccdef2828927EC2.4.1xref_analog2782452ReactomeREACT_22295Addition of a third mannose to the N-glycan precursor by Alg2, Saccharomyces cerevisiaexref_analog2808389OntologyLoader1.02017-03-09T16:31:20+01:00http://www.goontology.org/2017-03-09T16:30:51+01:00rootGO Ontolgy2017-03-09T00:00:00+01:00Inserted1.0226) linkage.GO:0000009falsealpha-1,6-mannosyltransferase activitymolecular_function26511412603725exact1,6-alpha-mannosyltransferase activity265114126511412603725exact26037252614534gosubset_prokProkaryotic GO subset2603714KEGGR05612def2797698KEGGR05612xref_analog2797699RHEA20839def2785008RHEA20839xref_analog2785009OntologyLoader1.02017-03-09T16:31:20+01:00http://www.goontology.org/2017-03-09T16:30:51+01:00rootGO Ontolgy2017-03-09T00:00:00+01:00Inserted1.022Catalysis of the reaction: all-trans-hexaprenyl diphosphate + isopentenyl diphosphate = all-trans-heptaprenyl diphosphate + diphosphate.GO:0000010falsetrans-hexaprenyltranstransferase activitymolecular_function2603726260938226301191087382414616069GOCmccdef2828927OntologyLoader1.02017-03-09T16:31:20+01:00http://www.goontology.org/2017-03-09T16:30:51+01:00rootGO Ontolgy2017-03-09T00:00:00+01:00Inserted1.022The distribution of vacuoles into daughter cells after mitosis or meiosis, mediated by interactions between vacuoles and the cytoskeleton.GO:0000011falsevacuole inheritancebiological_process26037272608716gosubset_prokProkaryotic GO subset2603714URLhttp://www.ultranet.com/~jkimball/BiologyPages/D/DNArepair.htmldef2828846OntologyLoader1.02017-03-09T16:31:20+01:00http://www.goontology.org/2017-03-09T16:30:51+01:00rootGO Ontolgy2017-03-09T00:00:00+01:00Inserted1.022The repair of single strand breaks in DNA. Repair of such breaks is mediated by the same enzyme systems as are used in base excision repair.GO:0000012falsesingle strand break repairbiological_process26037282607234GOCmahdef2828915OntologyLoader1.02017-03-09T16:31:20+01:00http://www.goontology.org/2017-03-09T16:30:51+01:00rootGO Ontolgy2017-03-09T00:00:00+01:00Inserted1.022Catalysis of the hydrolysis of ester linkages within a single-stranded deoxyribonucleic acid molecule by creating internal breaks.GO:0000014falsesingle-stranded DNA endodeoxyribonuclease activitymolecular_function27512922603729relatedsingle-stranded DNA specific endodeoxyribonuclease activity275129227512922603729related27520972603729relatedssDNA-specific endodeoxyribonuclease activity275209727520972603729related260372926265512644495goslim_metagenomicsMetagenomics GO slim2603706gosubset_prokProkaryotic GO subset2603714ISBN0198506732def2774934GOCjldef2828875OntologyLoader1.02017-03-09T16:31:20+01:00http://www.goontology.org/2017-03-09T16:30:51+01:00rootGO Ontolgy2017-03-09T00:00:00+01:00Inserted1.022A multimeric enzyme complex, usually a dimer or an octamer, that catalyzes the conversion of 2-phospho-D-glycerate to phosphoenolpyruvate and water.GO:0000015falsephosphopyruvate hydratase complexcellular_component27029952603730exactenolase complex270299527029952603730exact26037302607255ReactomeREACT_104113D-glucose + D-galactose, Rattus norvegicusxref_analog2800491ReactomeREACT_114967D-glucose + D-galactose, Drosophila melanogasterxref_analog2806056ReactomeREACT_100439D-glucose + D-galactose, Gallus gallusxref_analog2798445ReactomeREACT_109391D-glucose + D-galactose, Sus scrofaxref_analog2803394RHEA10079xref_analog2778273ReactomeREACT_109208D-glucose + D-galactose, Taeniopygia guttataxref_analog2803303ReactomeREACT_112431D-glucose + D-galactose, Caenorhabditis elegansxref_analog2804743ReactomeREACT_78754D-glucose + D-galactose, Xenopus tropicalisxref_analog2814042EC3.2.1.108def2787480EC3.2.1.108xref_analog2787481ReactomeREACT_9455D-glucose + D-galactose, Homo sapiensxref_analog2822808ReactomeREACT_105850D-glucose + D-galactose, Bos taurusxref_analog2801438ReactomeREACT_78084D-glucose + D-galactose, Canis familiarisxref_analog2813692ReactomeREACT_109447D-glucose + D-galactose, Danio rerioxref_analog2803421MetaCycLACTASE-RXNxref_analog2794738ReactomeREACT_30821D-glucose + D-galactose, Mus musculusxref_analog2810231OntologyLoader1.02017-03-09T16:31:20+01:00http://www.goontology.org/2017-03-09T16:30:51+01:00rootGO Ontolgy2017-03-09T00:00:00+01:00Inserted1.022Catalysis of the reaction: lactose + H2O = D-glucose + D-galactose.GO:0000016falselactase activitymolecular_function27167712603731broadlactase-phlorizin hydrolase activity271677127167712603731broad27168322603731exactlactose galactohydrolase activity271683227168322603731exact26037312625133ISBN0198506732def2774934GOCjldef2828875URLhttp://www.biochem.purdue.edu/def2828737OntologyLoader1.02017-03-09T16:31:20+01:00http://www.goontology.org/2017-03-09T16:30:51+01:00rootGO Ontolgy2017-03-09T00:00:00+01:00Inserted1.022The directed movement of alpha-glucosides into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Alpha-glucosides are glycosides in which the sugar group is a glucose residue, and the anomeric carbon of the bond is in an alpha configuration.GO:0000017falsealpha-glucoside transportbiological_process260373226317372608744regulatesgosubset_prokProkaryotic GO subset2603714ISBN0198506732def2774934GOCgo_curatorsdef2828596OntologyLoader1.02017-03-09T16:31:20+01:00http://www.goontology.org/2017-03-09T16:30:51+01:00rootGO Ontolgy2017-03-09T00:00:00+01:00Inserted1.022Any process that modulates the frequency, rate or extent of DNA recombination, a DNA metabolic process in which a new genotype is formed by reassortment of genes resulting in gene combinations different from those that were present in the parents.GO:0000018falseregulation of DNA recombinationbiological_process260373326037332608746regulatesGOCgo_curatorsdef2828596OntologyLoader1.02017-03-09T16:31:20+01:00http://www.goontology.org/2017-03-09T16:30:51+01:00rootGO Ontolgy2017-03-09T00:00:00+01:00Inserted1.022Any process that modulates the frequency, rate or extent of DNA recombination during mitosis.GO:0000019falseregulation of mitotic recombinationbiological_process27478682603734narrowregulation of recombination within rDNA repeats274786827478682603734narrow26037342627879ISBN0198506732def2774934GOCgo_curatorsdef2828596This term was made obsolete because it describes a substrate-specific process.OntologyLoader1.02017-03-09T16:31:20+01:00http://www.goontology.org/2017-03-09T16:30:51+01:00rootGO Ontolgy2017-03-09T00:00:00+01:00Inserted1.022OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of genetic recombination within the DNA of the genes coding for ribosomal RNA.GO:0000020trueobsolete negative regulation of recombination within rDNA repeatsbiological_process27267232603735exactnegative regulation of recombination within rDNA repeats272672327267232603735exact2603735263191226450432603774part_of2603965part_of2609399part_ofGOCmtg_cell_cycledef2828967GOCvwdef2830609OntologyLoader1.02017-03-09T16:31:20+01:00http://www.goontology.org/2017-03-09T16:30:51+01:00rootGO Ontolgy2017-03-09T00:00:00+01:00Inserted1.022The cell cycle process in which the distance is lengthened between poles of the mitotic spindle. Mitotic spindle elongation begins during mitotic prophase and ends during mitotic anaphase B.GO:0000022falsemitotic spindle elongationbiological_process27519262603736exactspindle elongation during mitosis275192627519262603736exact26037362608435gosubset_prokProkaryotic GO subset2603714ISBN0198506732def2774934GOCjldef2828875OntologyLoader1.02017-03-09T16:31:20+01:00http://www.goontology.org/2017-03-09T16:30:51+01:00rootGO Ontolgy2017-03-09T00:00:00+01:00Inserted1.022The chemical reactions and pathways involving the disaccharide maltose (4-O-alpha-D-glucopyranosyl-D-glucopyranose), an intermediate in the catabolism of glycogen and starch.GO:0000023falsemaltose metabolic processbiological_process27185562603737exactmalt sugar metabolism271855627185562603737exact27185552603737exactmalt sugar metabolic process271855527185552603737exact27185832603737exactmaltose metabolism271858327185832603737exact260373726037372628280gosubset_prokProkaryotic GO subset2603714ISBN0198506732def2774934GOCjldef2828875OntologyLoader1.02017-03-09T16:31:20+01:00http://www.goontology.org/2017-03-09T16:30:51+01:00rootGO Ontolgy2017-03-09T00:00:00+01:00Inserted1.022The chemical reactions and pathways resulting in the formation of the disaccharide maltose (4-O-alpha-D-glucopyranosyl-D-glucopyranose).GO:0000024falsemaltose biosynthetic processbiological_process27185762603738exactmaltose anabolism271857627185762603738exact27185862603738exactmaltose synthesis271858627185862603738exact27185802603738exactmaltose formation271858027185802603738exact27185522603738exactmalt sugar biosynthetic process271855227185522603738exact27185772603738exactmaltose biosynthesis271857727185772603738exact27185512603738exactmalt sugar biosynthesis271855127185512603738exact260373826037372628281gosubset_prokProkaryotic GO subset2603714ISBN0198506732def2774934GOCjldef2828875MetaCycMALTOSECAT-PWYxref_analog2794913OntologyLoader1.02017-03-09T16:31:20+01:00http://www.goontology.org/2017-03-09T16:30:51+01:00rootGO Ontolgy2017-03-09T00:00:00+01:00Inserted1.022The chemical reactions and pathways resulting in the breakdown of the disaccharide maltose (4-O-alpha-D-glucopyranosyl-D-glucopyranose).GO:0000025falsemaltose catabolic processbiological_process27185792603739exactmaltose degradation271857927185792603739exact27185782603739exactmaltose breakdown271857827185782603739exact27185822603739narrowmaltose hydrolysis271858227185822603739narrow27185542603739exactmalt sugar catabolism271855427185542603739exact27185532603739exactmalt sugar catabolic process271855327185532603739exact2603739260374310521541ReactomeREACT_22220Addition of the fourth and fifth mannose to the N-glycan precursor skeleton by Alg11, Saccharomyces cerevisiaexref_analog2808354ReactomeREACT_22123Addition of the seventh mannose to the N-glycan precursor by ALG9, inside the ER lumen, Homo sapiensxref_analog2808315ReactomeREACT_22156Addition of a fourth and fifth mannose to the N-glycan precursor by ALG11, Homo sapiensxref_analog2808323GOCmccdef2828927EC2.4.1xref_analog2782452ReactomeREACT_22307Addition of the last mannose to the N-glycan precursor by ALG3, inside the ER lumen., Homo sapiensxref_analog2808396OntologyLoader1.02017-03-09T16:31:20+01:00http://www.goontology.org/2017-03-09T16:30:51+01:00rootGO Ontolgy2017-03-09T00:00:00+01:00Inserted1.0222) linkage.GO:0000026falsealpha-1,2-mannosyltransferase activitymolecular_function260374026173292624482part_of2624496part_ofgosubset_prokProkaryotic GO subset2603714GOCjldef2828875GOCmahdef2828915OntologyLoader1.02017-03-09T16:31:20+01:00http://www.goontology.org/2017-03-09T16:30:51+01:00rootGO Ontolgy2017-03-09T00:00:00+01:00Inserted1.022The aggregation, arrangement and bonding together of constituent RNAs and proteins to form the large ribosomal subunit.GO:0000027falseribosomal large subunit assemblybiological_process26542462603741narrow60S ribosomal subunit assembly265424626542462603741narrow26540652603741narrow50S ribosomal subunit assembly265406526540652603741narrow260374126173292624482part_of2624497part_ofgosubset_prokProkaryotic GO subset2603714GOCjldef2828875GOCmahdef2828915OntologyLoader1.02017-03-09T16:31:20+01:00http://www.goontology.org/2017-03-09T16:30:51+01:00rootGO Ontolgy2017-03-09T00:00:00+01:00Inserted1.022The aggregation, arrangement and bonding together of constituent RNAs and proteins to form the small ribosomal subunit.GO:0000028falseribosomal small subunit assemblybiological_process26531552603742narrow30S ribosomal subunit assembly265315526531552603742narrow26536882603742narrow40S ribosomal subunit assembly265368826536882603742narrow26037422614527gosubset_prokProkaryotic GO subset2603714ReactomeREACT_22117Addition of the eighth mannose to the N-glycan precursor by ALG12, inside the ER lumen, Homo sapiensxref_analog2808313ReactomeREACT_105204mannose(al1-4)glucosaminyl-acyl-PI + dolichol phosphate, Dictyostelium discoideumxref_analog2801086ReactomeREACT_2179mannose (a1) mannose (a1-2) mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI, Homo sapiensxref_analog2808284GOCcjmdef2828332ReactomeREACT_30252mannose(al1-4)glucosaminyl-acyl-PI + dolichol phosphate, Rattus norvegicusxref_analog2809938ReactomeREACT_34702mannose(al1-4)glucosaminyl-acyl-PI + dolichol phosphate, Danio rerioxref_analog2812226ReactomeREACT_87972mannose(al1-4)glucosaminyl-acyl-PI + dolichol phosphate, Canis familiarisxref_analog2819137ReactomeREACT_95740mannose(al1-4)glucosaminyl-acyl-PI + dolichol phosphate, Gallus gallusxref_analog2823521GOCaidef2828262EC2.4.1xref_analog2782452ReactomeREACT_1018mannose(al1-4)glucosaminyl-acyl-PI + dolichol phosphate, Homo sapiensxref_analog2799236ReactomeREACT_63412mannose(al1-4)glucosaminyl-acyl-PI + dolichol phosphate, Mus musculusxref_analog2812724OntologyLoader1.02017-03-09T16:31:20+01:00http://www.goontology.org/2017-03-09T16:30:51+01:00rootGO Ontolgy2017-03-09T00:00:00+01:00Inserted1.022Catalysis of the transfer of a mannosyl group to an acceptor molecule, typically another carbohydrate or a lipid.GO:0000030falsemannosyltransferase activitymolecular_function26037432614510GOCjldef2828875OntologyLoader1.02017-03-09T16:31:20+01:00http://www.goontology.org/2017-03-09T16:30:51+01:00rootGO Ontolgy2017-03-09T00:00:00+01:00Inserted1.022Catalysis of the transfer of a mannosylphosphate group from one compound to another.GO:0000031falsemannosylphosphate transferase activitymolecular_function260374426085062618867gosubset_prokProkaryotic GO subset2603714GOCaidef2828262OntologyLoader1.02017-03-09T16:31:20+01:00http://www.goontology.org/2017-03-09T16:30:51+01:00rootGO Ontolgy2017-03-09T00:00:00+01:00Inserted1.022The chemical reactions and pathways resulting in the formation of cell wall mannoproteins, any cell wall protein that contains covalently bound mannose residues.GO:0000032falsecell wall mannoprotein biosynthetic processbiological_process26811302603745exactcell wall mannoprotein synthesis268113026811302603745exact26811292603745exactcell wall mannoprotein formation268112926811292603745exact26811282603745exactcell wall mannoprotein biosynthesis268112826811282603745exact26811272603745exactcell wall mannoprotein anabolism268112726811272603745exact2603745260374310521541ReactomeREACT_22347Addition of a second mannose to the N-glycan precursor by ALG2, Homo sapiensxref_analog2808414GOCmccdef2828927EC2.4.1xref_analog2782452ReactomeREACT_22415Addition of the sixth mannose to the N-glycan precursor by ALG3., Homo sapiensxref_analog2808444OntologyLoader1.02017-03-09T16:31:20+01:00http://www.goontology.org/2017-03-09T16:30:51+01:00rootGO Ontolgy2017-03-09T00:00:00+01:00Inserted1.0223) linkage.GO:0000033falsealpha-1,3-mannosyltransferase activitymolecular_function260374626145762616035gosubset_prokProkaryotic GO subset2603714RHEA23691xref_analog2785907EC3.5.4.2def2788742MetaCycADENINE-DEAMINASE-RXNxref_analog2792454EC3.5.4.2xref_analog2788743OntologyLoader1.02017-03-09T16:31:20+01:00http://www.goontology.org/2017-03-09T16:30:51+01:00rootGO Ontolgy2017-03-09T00:00:00+01:00Inserted1.022Catalysis of the reaction: adenine + H2O = hypoxanthine + NH3.GO:0000034falseadenine deaminase activitymolecular_function26754222603747exactadenase activity267542226754222603747exact26546342603747exactADase activity265463426546342603747exact26754242603747exactadenine aminohydrolase activity267542426754242603747exact26754232603747exactadenine aminase activity267542326754232603747exact26037472607995gosubset_prokProkaryotic GO subset2603714ISBN0198506732def2774934GOCcuratorsdef2828351OntologyLoader1.02017-03-09T16:31:20+01:00http://www.goontology.org/2017-03-09T16:30:51+01:00rootGO Ontolgy2017-03-09T00:00:00+01:00Inserted1.022Interacting selectively and non-covalently with an acyl group, any group formally derived by removal of the hydroxyl group from the acid function of a carboxylic acid.GO:0000035falseacyl bindingmolecular_function26752562603748broadacyl-CoA or acyl binding267525626752562603748broad26037482626726gosubset_prokProkaryotic GO subset2603714CHEBI22221def2785422GOCjldef2828875GOCvwdef2830609Note that this term was moved from transporter to binding because we decided that ACP is not a true transporter, but instead tethers the growing entity that is acted on to make the fatty acid, so binding is the more correct parent. July 2012.OntologyLoader1.02017-03-09T16:31:20+01:00http://www.goontology.org/2017-03-09T16:30:51+01:00rootGO Ontolgy2017-03-09T00:00:00+01:00Inserted1.022Interacting selectively and non-covalently with the attachment site of the phosphopantetheine prosthetic group of an acyl carrier protein (ACP) as part of the process of fatty acid biosynthesis.GO:0000036falseACP phosphopantetheine attachment site binding involved in fatty acid biosynthetic processmolecular_function26752202603749exactacyl carrier activity267522026752202603749exact26037492609029gosubset_prokProkaryotic GO subset2603714CHEBI27283def2786472GOCbfdef2828296GOChjddef2828608OntologyLoader1.02017-03-09T16:31:20+01:00http://www.goontology.org/2017-03-09T16:30:51+01:00rootGO Ontolgy2017-03-09T00:00:00+01:00Inserted1.022The chemical reactions and pathways involving a fatty acid which has a chain length greater than C22.GO:0000038falsevery long-chain fatty acid metabolic processbiological_process27732192603750exactvery long chain fatty acid metabolic process277321927732192603750exact27732452603750exactvery-long-chain fatty acid metabolism277324527732452603750exact27732442603750exactvery-long-chain fatty acid metabolic process277324427732442603750exact260375026079102608345GOCaidef2828262This term was made obsolete because it describes a gene product and it contains component information.OntologyLoader1.02017-03-09T16:31:20+01:00http://www.goontology.org/2017-03-09T16:30:51+01:00rootGO Ontolgy2017-03-09T00:00:00+01:00Inserted1.022OBSOLETE (was not defined before being made obsolete).GO:0000039trueobsolete plasma membrane long-chain fatty acid transportermolecular_function27323092603751exactplasma membrane long-chain fatty acid transporter273230927323092603751exact26037512622020GOCmahdef2828915OntologyLoader1.02017-03-09T16:31:20+01:00http://www.goontology.org/2017-03-09T16:30:51+01:00rootGO Ontolgy2017-03-09T00:00:00+01:00Inserted1.022A process in which an iron ion is transported from one side of a membrane to the other by means of some agent such as a transporter or pore. In low-affinity transport the transporter is able to bind the solute only if it is only present at very low concentrations.GO:0000040falselow-affinity iron ion transmembrane transportbiological_process27177252603752broadlow affinity iron ion transport271772527177252603752broad27177452603752broadlow-affinity iron ion transport271774527177452603752broad26037522617470gosubset_prokProkaryotic GO subset2603714ISBN0198506732def2774934OntologyLoader1.02017-03-09T16:31:20+01:00http://www.goontology.org/2017-03-09T16:30:51+01:00rootGO Ontolgy2017-03-09T00:00:00+01:00Inserted1.022The directed movement of transition metal ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. A transition metal is an element whose atom has an incomplete d-subshell of extranuclear electrons, or which gives rise to a cation or cations with an incomplete d-subshell. Transition metals often have more than one valency state. Biologically relevant transition metals include vanadium, manganese, iron, copper, cobalt, nickel, molybdenum and silver.GO:0000041falsetransition metal ion transportbiological_process27558502603753exacttransition metal transport275585027558502603753exact2603753260398726090032638084GOCmahdef2828915GOCaidef2828262OntologyLoader1.02017-03-09T16:31:20+01:00http://www.goontology.org/2017-03-09T16:30:51+01:00rootGO Ontolgy2017-03-09T00:00:00+01:00Inserted1.022The process of directing proteins towards the Golgi; usually uses signals contained within the protein.GO:0000042falseprotein targeting to Golgibiological_process27408102603754exactprotein-Golgi targeting274081027408102603754exact2603754GOCaidef2828262GOCmtg_electron_transportdef2828969This term was made obsolete because it is defined as a function term and is in the process ontology.OntologyLoader1.02017-03-09T16:31:20+01:00http://www.goontology.org/2017-03-09T16:30:51+01:00rootGO Ontolgy2017-03-09T00:00:00+01:00Inserted1.022OBSOLETE. The reduction of the ascorbate free radical to a stable form.GO:0000044trueobsolete ascorbate stabilizationbiological_process27737892603755exactvitamin C stabilization277378927737892603755exact26778872603755exactascorbate stabilization267788726778872603755exact2603755263645426470029412464GOCautophagydef2828291GOCmahdef2828915OntologyLoader1.02017-03-09T16:31:20+01:00http://www.goontology.org/2017-03-09T16:30:51+01:00rootGO Ontolgy2017-03-09T00:00:00+01:00Inserted1.022The formation of a double membrane-bounded structure, the autophagosome, that occurs when a specialized membrane sac, called the isolation membrane, starts to enclose a portion of the cytoplasm.GO:0000045falseautophagosome assemblybiological_process26646372603756narrowPAS formation266463726646372603756narrow26783152603756exactautophagosome formation267831526783152603756exact26783142603756exactautophagosome biosynthesis267831426783142603756exact26783022603756exactautophagic vacuole assembly267830226783022603756exact26783042603756relatedautophagic vacuole formation267830426783042603756related26037562610882GOCaidef2828262This term was made obsolete because it represents a gene product.OntologyLoader1.02017-03-09T16:31:20+01:00http://www.goontology.org/2017-03-09T16:30:51+01:00rootGO Ontolgy2017-03-09T00:00:00+01:00Inserted1.022OBSOLETE (was not defined before being made obsolete).GO:0000047trueobsolete Rieske iron-sulfur proteinmolecular_function26657912603757exactRieske iron-sulphur protein266579126657912603757exact26657902603757exactRieske iron-sulfur protein266579026657902603757exact26037572614524114333659242921ReactomeREACT_90457Peptide transfer from P-site tRNA to the A-site tRNA, Canis familiarisxref_analog2820527ReactomeREACT_102632Peptide transfer from P-site tRNA to the A-site tRNA, Saccharomyces cerevisiaexref_analog2799695ReactomeREACT_1227Peptide transfer from P-site tRNA to the A-site tRNA, Homo sapiensxref_analog2806989ReactomeREACT_90185Peptide transfer from P-site tRNA to the A-site tRNA, Danio rerioxref_analog2820364ReactomeREACT_31656Peptide transfer from P-site tRNA to the A-site tRNA, Taeniopygia guttataxref_analog2810658ReactomeREACT_115501Peptide transfer from P-site tRNA to the A-site tRNA, Rattus norvegicusxref_analog2806337ReactomeREACT_91228Peptide transfer from P-site tRNA to the A-site tRNA, Caenorhabditis elegansxref_analog2820960ReactomeREACT_33679Peptide transfer from P-site tRNA to the A-site tRNA, Dictyostelium discoideumxref_analog2811717ReactomeREACT_98179Peptide transfer from P-site tRNA to the A-site tRNA, Xenopus tropicalisxref_analog2824868EC2.3.2.12xref_analog2782394MetaCycPEPTIDYLTRANSFERASE-RXNxref_analog2795482ReactomeREACT_77497Peptide transfer from P-site tRNA to the A-site tRNA, Oryza sativaxref_analog2813371EC2.3.2.12def2782393ReactomeREACT_95405Peptide transfer from P-site tRNA to the A-site tRNA, Plasmodium falciparumxref_analog2823325ReactomeREACT_104123Peptide transfer from P-site tRNA to the A-site tRNA, Schizosaccharomyces pombexref_analog2800496ReactomeREACT_112282Peptide transfer from P-site tRNA to the A-site tRNA, Gallus gallusxref_analog2804657ReactomeREACT_28090Peptide transfer from P-site tRNA to the A-site tRNA, Arabidopsis thalianaxref_analog2808881ReactomeREACT_81539Peptide transfer from P-site tRNA to the A-site tRNA, Drosophila melanogasterxref_analog2815607ReactomeREACT_87719Peptide transfer from P-site tRNA to the A-site tRNA, Mus musculusxref_analog2818997OntologyLoader1.02017-03-09T16:31:20+01:00http://www.goontology.org/2017-03-09T16:30:51+01:00rootGO Ontolgy2017-03-09T00:00:00+01:00Inserted1.022Catalysis of the reaction: peptidyl-tRNA(1) + aminoacyl-tRNA(2) = tRNA(1) + peptidylaminoacyl-tRNA(2).GO:0000048falsepeptidyltransferase activitymolecular_function27309412603758exactpeptidyl-tRNA:aminoacyl-tRNA N-peptidyltransferase activity273094127309412603758exact26037582606544gosubset_prokProkaryotic GO subset2603714GOCaidef2828262OntologyLoader1.02017-03-09T16:31:20+01:00http://www.goontology.org/2017-03-09T16:30:51+01:00rootGO Ontolgy2017-03-09T00:00:00+01:00Inserted1.022Interacting selectively and non-covalently with transfer RNA.GO:0000049falsetRNA bindingmolecular_function2603759GO:0006594GO:00068712616405262573226268162643588ReactomeREACT_107747Urea cycle, Mus musculusxref_analog2802474ReactomeREACT_81058Urea cycle, Dictyostelium discoideumxref_analog2815337ReactomeREACT_83831Urea cycle, Rattus norvegicusxref_analog2816878ReactomeREACT_95880Urea cycle, Staphylococcus aureus N315xref_analog2823597ReactomeREACT_33119Urea cycle, Bos taurusxref_analog2811427ReactomeREACT_97366Urea cycle, Arabidopsis thalianaxref_analog2824418ReactomeREACT_31787Urea cycle, Taeniopygia guttataxref_analog2810726ReactomeREACT_80089Urea cycle, Canis familiarisxref_analog2814779ReactomeREACT_88394Urea cycle, Gallus gallusxref_analog2819386ReactomeREACT_98985Urea cycle, Schizosaccharomyces pombexref_analog2825337ReactomeREACT_84694Urea cycle, Saccharomyces cerevisiaexref_analog2817342ReactomeREACT_90565Urea cycle, Sus scrofaxref_analog2820597ReactomeREACT_100599Urea cycle, Oryza sativaxref_analog2798538WikipediaUrea_cyclexref_analog2828171ReactomeREACT_32463Urea cycle, Drosophila melanogasterxref_analog2811083ReactomeREACT_32971Urea cycle, Caenorhabditis elegansxref_analog2811341ReactomeREACT_847Urea cycle, Homo sapiensxref_analog2817345ReactomeREACT_92378Urea cycle, Xenopus tropicalisxref_analog2821574ReactomeREACT_109525Urea cycle, Danio rerioxref_analog2803461ReactomeREACT_82995Urea cycle, Mycobacterium tuberculosisxref_analog2816410GOCpdedef2829087ReactomeREACT_90218Urea cycle, Escherichia colixref_analog2820382ReactomeREACT_78616Urea cycle, Plasmodium falciparumxref_analog2813968GOCvwdef2830609ISBN0198506732def2774934OntologyLoader1.02017-03-09T16:31:20+01:00http://www.goontology.org/2017-03-09T16:30:51+01:00rootGO Ontolgy2017-03-09T00:00:00+01:00Inserted1.022The sequence of reactions by which arginine is synthesized from ornithine, then cleaved to yield urea and regenerate ornithine. The overall reaction equation is NH3 + CO2 + aspartate + 3 ATP + 2 H2O = urea + fumarate + 2 ADP + 2 phosphate + AMP + diphosphate.GO:0000050falseurea cyclebiological_process27726432603760exacturea biosynthesis277264327726432603760exact27295882603760exactornithine cycle272958827295882603760exact27726442603760exacturea biosynthetic process277264427726442603760exact2603760gosubset_prokProkaryotic GO subset2603714ISBN0198506732def2774934GOCjldef2828875This term was made obsolete because it is a grouping term that is not useful, but has caused true path violations.OntologyLoader1.02017-03-09T16:31:20+01:00http://www.goontology.org/2017-03-09T16:30:51+01:00rootGO Ontolgy2017-03-09T00:00:00+01:00Inserted1.022OBSOLETE. The chemical reactions and pathways involving any of the intermediate compounds involved in the urea cycle, a cyclic metabolic pathway that converts waste nitrogen in the form of ammonium to urea.GO:0000051trueobsolete urea cycle intermediate metabolic processbiological_process27726502603761exacturea cycle intermediate metabolism277265027726502603761exact27726492603761exacturea cycle intermediate metabolic process277264927726492603761exact26037612643626gosubset_prokProkaryotic GO subset2603714ISBN0198506732def2774934OntologyLoader1.02017-03-09T16:31:20+01:00http://www.goontology.org/2017-03-09T16:30:51+01:00rootGO Ontolgy2017-03-09T00:00:00+01:00Inserted1.022The chemical reactions and pathways involving citrulline, N5-carbamoyl-L-ornithine, an alpha amino acid not found in proteins.GO:0000052falsecitrulline metabolic processbiological_process26830332603762exactcitrulline metabolism268303326830332603762exact2603762260897426378602643626ISBN0198506732def2774934OntologyLoader1.02017-03-09T16:31:20+01:00http://www.goontology.org/2017-03-09T16:30:51+01:00rootGO Ontolgy2017-03-09T00:00:00+01:00Inserted1.022The chemical reactions and pathways involving argininosuccinate, 2-(N(omega)-arginino)succinate, an intermediate in the ornithine-urea cycle, where it is synthesized from citrulline and aspartate.GO:0000053falseargininosuccinate metabolic processbiological_process26777012603763exactargininosuccinate metabolism267770126777012603763exact2603763262103826369562624481part_ofgoslim_yeastYeast GO slim2603713GOCmahdef2828915GOCaidef2828262GOCrbdef2830181OntologyLoader1.02017-03-09T16:31:20+01:00http://www.goontology.org/2017-03-09T16:30:51+01:00rootGO Ontolgy2017-03-09T00:00:00+01:00Inserted1.022The directed movement of a ribosomal subunit from the nucleus into the cytoplasm.GO:0000054falseribosomal subunit export from nucleusbiological_process27500682603764exactribosomal subunit-nucleus export275006827500682603764exact27500712603764relatedribosome export from nucleus275007127500712603764related27500672603764exactribosomal subunit transport from nucleus to cytoplasm275006727500672603764exact27500662603764exactribosomal subunit export out of nucleus275006627500662603764exact27500652603764exactribosomal subunit export from cell nucleus275006527500652603764exact2603764GO:00000572603764GOCmahdef2828915OntologyLoader1.02017-03-09T16:31:20+01:00http://www.goontology.org/2017-03-09T16:30:51+01:00rootGO Ontolgy2017-03-09T00:00:00+01:00Inserted1.022The directed movement of a ribosomal large subunit from the nucleus into the cytoplasm.GO:0000055falseribosomal large subunit export from nucleusbiological_process27500462603765exactribosomal large subunit-nucleus export275004627500462603765exact27500452603765exactribosomal large subunit transport from nucleus to cytoplasm275004527500452603765exact26540662603765narrow50S ribosomal subunit export from nucleus265406626540662603765narrow26542472603765narrow60S ribosomal subunit export from nucleus265424726542472603765narrow27500442603765exactribosomal large subunit export out of nucleus275004427500442603765exact27500432603765exactribosomal large subunit export from cell nucleus275004327500432603765exact2603765GO:00000582603764GOCmahdef2828915OntologyLoader1.02017-03-09T16:31:20+01:00http://www.goontology.org/2017-03-09T16:30:51+01:00rootGO Ontolgy2017-03-09T00:00:00+01:00Inserted1.022The directed movement of a ribosomal small subunit from the nucleus into the cytoplasm.GO:0000056falseribosomal small subunit export from nucleusbiological_process27500602603766exactribosomal small subunit export from cell nucleus275006027500602603766exact26536892603766narrow40S ribosomal subunit export from nucleus265368926536892603766narrow26531562603766narrow30S ribosomal subunit export from nucleus265315626531562603766narrow27500632603766exactribosomal small subunit-nucleus export275006327500632603766exact27500622603766exactribosomal small subunit transport from nucleus to cytoplasm275006227500622603766exact27500612603766exactribosomal small subunit export out of nucleus275006127500612603766exact26037667878057912673614570049GOCmahdef2828915GOCisa_completedef2828864This term was made obsolete because the transient assembly is better captured as a protein-protein association, if at all.OntologyLoader1.02017-03-09T16:31:20+01:00http://www.goontology.org/2017-03-09T16:30:51+01:00rootGO Ontolgy2017-03-09T00:00:00+01:00Inserted1.022OBSOLETE. A protein complex assembly process that contributes to protein import into the nucleus, and that results in the association of a cargo protein, a carrier protein such as an importin alpha/beta heterodimer, and a nucleoporin located at the periphery of the nuclear pore complex.GO:0000059trueobsolete protein import into nucleus, dockingbiological_process27400492603767exactprotein docking during protein import into nucleus274004927400492603767exact27409022603767exactprotein-nucleus import, docking274090227409022603767exact27407482603767exactprotein transport from cytoplasm to nucleus, docking274074827407482603767exact27400532603767exactprotein docking during protein-nucleus import274005327400532603767exact27400512603767exactprotein docking during protein transport from cytoplasm to nucleus274005127400512603767exact260376726092599126736145700492609004part_ofISBN0198506732def2774934GOCcuratorsdef2828351Note that 'vectorial' is used in the definition in the mathematical and physical sense of pertaining to 'a quantity having direction as well as magnitude, especially as determining the position of one point in space relative to another. Note that 'translocation' is sometimes used in the literature to refer to the entire process of protein import into the nucleus, but in GO refers specifically to the step in which a cargo-carrier protein complex moves through the nuclear pore complex.OntologyLoader1.02017-03-09T16:31:20+01:00http://www.goontology.org/2017-03-09T16:30:51+01:00rootGO Ontolgy2017-03-09T00:00:00+01:00Inserted1.022A protein transport process that contributes to protein import into the nucleus, and that results in the vectorial transfer of a cargo-carrier protein complex through the nuclear pore complex from the cytoplasmic side to the nucleoplasmic side of the nuclear envelope.GO:0000060falseprotein import into nucleus, translocationbiological_process27407502603768exactprotein transport from cytoplasm to nucleus, translocation274075027407502603768exact27409042603768exactprotein-nucleus import, translocation274090427409042603768exact27401062603768exactprotein import into cell nucleus, translocation274010627401062603768exact27407422603768exactprotein translocation during protein-nucleus import274074227407422603768exact27407402603768exactprotein translocation during protein transport from cytoplasm to nucleus274074027407402603768exact27407382603768exactprotein translocation during protein import into nucleus274073827407382603768exact2603768262575291267369687515145700492609004part_ofGOCmahdef2828915OntologyLoader1.02017-03-09T16:31:20+01:00http://www.goontology.org/2017-03-09T16:30:51+01:00rootGO Ontolgy2017-03-09T00:00:00+01:00Inserted1.022A protein complex disassembly process that contributes to protein import into the nucleus, and that results in the dissociation of the cargo protein and the carrier (such as an importin alpha/beta heterodimer) from each other and from the nuclear pore complex.GO:0000061falseprotein import into nucleus, substrate releasebiological_process27407492603769exactprotein transport from cytoplasm to nucleus, substrate release274074927407492603769exact27409032603769exactprotein-nucleus import, substrate release274090327409032603769exact27401052603769exactprotein import into cell nucleus, substrate release274010527401052603769exact27407012603769exactprotein substrate release during protein-nucleus import274070127407012603769exact27407002603769exactprotein substrate release during protein transport from cytoplasm to nucleus274070027407002603769exact27406992603769exactprotein substrate release during protein import into nucleus274069927406992603769exact2603769262533526313532643701gosubset_prokProkaryotic GO subset2603714ISBN0198506732def2774934GOCjldef2828875OntologyLoader1.02017-03-09T16:31:20+01:00http://www.goontology.org/2017-03-09T16:30:51+01:00rootGO Ontolgy2017-03-09T00:00:00+01:00Inserted1.022Interacting selectively and non-covalently with acyl-CoA, any derivative of coenzyme A in which the sulfhydryl group is in thiolester linkage with a fatty acyl group.GO:0000062falsefatty-acyl-CoA bindingmolecular_function26752562603770broadacyl-CoA or acyl binding267525626752562603770broad260377026102302613158gosubset_prokProkaryotic GO subset2603714ReactomeREACT_102399ornithine (mitochondrial) + citrulline (cytosolic), Xenopus tropicalisxref_analog2799562ReactomeREACT_151ornithine (mitochondrial) + citrulline (cytosolic), Homo sapiensxref_analog2807433ReactomeREACT_78308ornithine (mitochondrial) + citrulline (cytosolic), Dictyostelium discoideumxref_analog2813807ReactomeREACT_100602ornithine (mitochondrial) + citrulline (cytosolic), Mus musculusxref_analog2798540ReactomeREACT_109285ornithine (mitochondrial) + citrulline (cytosolic), Caenorhabditis elegansxref_analog2803340ReactomeREACT_84383ornithine (mitochondrial) + citrulline (cytosolic), Oryza sativaxref_analog2817190GOCaidef2828262ReactomeREACT_104169ornithine (mitochondrial) + citrulline (cytosolic), Sus scrofaxref_analog2800517ReactomeREACT_28177ornithine (mitochondrial) + citrulline (cytosolic), Drosophila melanogasterxref_analog2808920ReactomeREACT_30708ornithine (mitochondrial) + citrulline (cytosolic), Arabidopsis thalianaxref_analog2810169ISBN0815340729def2775103ReactomeREACT_88959ornithine (mitochondrial) + citrulline (cytosolic), Rattus norvegicusxref_analog2819678ReactomeREACT_103552ornithine (mitochondrial) + citrulline (cytosolic), Gallus gallusxref_analog2800178ReactomeREACT_103610ornithine (mitochondrial) + citrulline (cytosolic), Canis familiarisxref_analog2800211ReactomeREACT_90007ornithine (mitochondrial) + citrulline (cytosolic), Taeniopygia guttataxref_analog2820274ReactomeREACT_115531ornithine (mitochondrial) + citrulline (cytosolic), Gallus gallusxref_analog2806352GOCmtg_transportdef2828983ReactomeREACT_88886ornithine (mitochondrial) + citrulline (cytosolic), Danio rerioxref_analog2819636OntologyLoader1.02017-03-09T16:31:20+01:00http://www.goontology.org/2017-03-09T16:30:51+01:00rootGO Ontolgy2017-03-09T00:00:00+01:00Inserted1.022Enables the transfer of L-ornithine from one side of a membrane to the other. L-ornithine is 2,5-diaminopentanoic acid.GO:0000064falseL-ornithine transmembrane transporter activitymolecular_function27085002603771relatedhistidine/arginine/lysine/ornithine porter activity270850027085002603771related26616862603771broadL-ornithine transporter activity266168626616862603771broad260377126092182613730GOCaidef2828262OntologyLoader1.02017-03-09T16:31:20+01:00http://www.goontology.org/2017-03-09T16:30:51+01:00rootGO Ontolgy2017-03-09T00:00:00+01:00Inserted1.022The directed movement of ornithine, 2,5-diaminopentanoic acid, into, out of or within a mitochondrion.GO:0000066falsemitochondrial ornithine transportbiological_process2603772260869726094062631954GOCaidef2828262This term was made obsolete because it has been superseded by more accurate terms to represent the biological processes occurring, and it is not clear that this term represents a useful entity.OntologyLoader1.02017-03-09T16:31:20+01:00http://www.goontology.org/2017-03-09T16:30:51+01:00rootGO Ontolgy2017-03-09T00:00:00+01:00Inserted1.022OBSOLETE (was not defined before being made obsolete).GO:0000067trueobsolete DNA replication and chromosome cyclebiological_process26577722603773exactDNA replication and chromosome cycle265777226577722603773exact2603773GO:0016359260428426450432603965part_of2609413part_ofgoslim_pombeFission yeast GO slim2603710GOCjldef2828875GOCaidef2828262OntologyLoader1.02017-03-09T16:31:20+01:00http://www.goontology.org/2017-03-09T16:30:51+01:00rootGO Ontolgy2017-03-09T00:00:00+01:00Inserted1.022The cell cycle process in which replicated homologous chromosomes are organized and then physically separated and apportioned to two sets during the mitotic cell cycle. Each replicated chromosome, composed of two sister chromatids, aligns at the cell equator, paired with its homologous partner. One homolog of each morphologic type goes into each of the resulting chromosome sets.GO:0000070falsemitotic sister chromatid segregationbiological_process27205872603774exactmitotic chromosome segregation272058727205872603774exact27206212603774narrowmitotic sister-chromatid adhesion release272062127206212603774narrow26037742609369GOCmahdef2828915This term was made obsolete because terms already exist for centrosome/spindle organization which would be more suitable for the existing annotations, and the phase could be captured as an annotation extension if necessary.OntologyLoader1.02017-03-09T16:31:20+01:00http://www.goontology.org/2017-03-09T16:30:51+01:00rootGO Ontolgy2017-03-09T00:00:00+01:00Inserted1.022OBSOLETE. A microtubule-based process that occurs only during M phase of the cell cycle.GO:0000072trueobsolete M phase specific microtubule processbiological_process26622152603775exactM-phase specific microtubule process266221526622152603775exact26621972603775exactM phase specific microtubule process266219726621972603775exact2603775GO:003047526172962631976part_ofGOCsgd_curatorsdef2830554OntologyLoader1.02017-03-09T16:31:20+01:00http://www.goontology.org/2017-03-09T16:30:51+01:00rootGO Ontolgy2017-03-09T00:00:00+01:00Inserted1.022A largely uncharacterized process involving the release of duplicated spindle pole bodies (SPBs) and their migration away from each other within the nuclear membrane. Duplicated SPBs are connected by a bridge structure that may be severed in order to release the SPBs from one another. Following liberation, SPBs diffuse through the nuclear membrane until they are across from each other. SPB separation must take place in order for a bipolar mitotic spindle to assemble.GO:0000073falsespindle pole body separationbiological_process2603776GO:0031576GO:007177926117642627733gocheck_do_not_manually_aTerm not to be used for d2603700ReactomeREACT_31789Cell Cycle Checkpoints, Dictyostelium discoideumxref_analog2810728ReactomeREACT_84460Cell Cycle Checkpoints, Arabidopsis thalianaxref_analog2817225ReactomeREACT_96499Cell Cycle Checkpoints, Taeniopygia guttataxref_analog2823944ReactomeREACT_109101Cell Cycle Checkpoints, Drosophila melanogasterxref_analog2803244ReactomeREACT_33305Cell Cycle Checkpoints, Oryza sativaxref_analog2811522ReactomeREACT_90285Cell Cycle Checkpoints, Mus musculusxref_analog2820419GOCmtg_cell_cycledef2828967ReactomeREACT_79078Cell Cycle Checkpoints, Sus scrofaxref_analog2814215ReactomeREACT_102145Cell Cycle Checkpoints, Saccharomyces cerevisiaexref_analog2799429ReactomeREACT_99737Cell Cycle Checkpoints, Schizosaccharomyces pombexref_analog2825764ReactomeREACT_92239Cell Cycle Checkpoints, Danio rerioxref_analog2821499ReactomeREACT_100401Cell Cycle Checkpoints, Gallus gallusxref_analog2798424WikipediaCell_cycle_checkpointxref_analog2793209ReactomeREACT_89660Cell Cycle Checkpoints, Xenopus tropicalisxref_analog2820062ReactomeREACT_1538Cell Cycle Checkpoints, Homo sapiensxref_analog2807507ReactomeREACT_29957Cell Cycle Checkpoints, Bos taurusxref_analog2809811ReactomeREACT_106487Cell Cycle Checkpoints, Rattus norvegicusxref_analog2801776ReactomeREACT_90465Cell Cycle Checkpoints, Caenorhabditis elegansxref_analog2820533ReactomeREACT_102175Cell Cycle Checkpoints, Canis familiarisxref_analog2799445This term should not be used in direct manual annotation as it should always be possible to minimally designate mitotic or meiotic checkpoint, and usually to additionally specify the checkpoint (i.e mitotic spindle assembly checkpoint, mitotic DNA damage checkpoint etc). Note also that the effector processes are not part of the checkpoint but are positively regulated by the checkpoint signaling and should not be annotated here.OntologyLoader1.02017-03-09T16:31:20+01:00http://www.goontology.org/2017-03-09T16:30:51+01:00rootGO Ontolgy2017-03-09T00:00:00+01:00Inserted1.022A cell cycle process that controls cell cycle progression by monitoring the integrity of specific cell cycle events. A cell cycle checkpoint begins with detection of deficiencies or defects and ends with signal transduction.GO:0000075falsecell cycle checkpointbiological_process26590222603777narrowG2/M transition checkpoint265902226590222603777narrow26589952603777narrowG1/S transition checkpoint265899526589952603777narrow26589932603777narrowG1/S checkpoint265899326589932603777narrow26590172603777narrowG2/M checkpoint265901726590172603777narrow260377726189291172832712537518GOCcuratorsdef2828351GOCrndef2830190OntologyLoader1.02017-03-09T16:31:20+01:00http://www.goontology.org/2017-03-09T16:30:51+01:00rootGO Ontolgy2017-03-09T00:00:00+01:00Inserted1.022A cell cycle checkpoint that prevents the initiation of nuclear division until DNA replication is complete, thereby ensuring that progeny inherit a full complement of the genome.GO:0000076falseDNA replication checkpointbiological_process260377826093342618929GOCmtg_cell_cycledef2828967WikipediaPostreplication_checkpointxref_analog2796163WikipediaDNA_damage_checkpointxref_analog2793489OntologyLoader1.02017-03-09T16:31:20+01:00http://www.goontology.org/2017-03-09T16:30:51+01:00rootGO Ontolgy2017-03-09T00:00:00+01:00Inserted1.022A cell cycle checkpoint that regulates progression through the cell cycle in response to DNA damage. A DNA damage checkpoint may blocks cell cycle progression (in G1, G2 or metaphase) or slow the rate at which S phase proceeds.GO:0000077falseDNA damage checkpointbiological_process26576382603779narrowDNA damage response, signal transduction resulting in cell cycle arrest265763826576382603779narrow260377926269812626982GOCmtg_cell_cycledef2828967GOCdphdef2828394GOCvwdef2830609The reason this term was made obsolete is that the two terms cytokinesis checkpoint (GO:0031565) and cytokinesis after mitosis (GO:0000078) were conflated in meaning.OntologyLoader1.02017-03-09T16:31:20+01:00http://www.goontology.org/2017-03-09T16:30:51+01:00rootGO Ontolgy2017-03-09T00:00:00+01:00Inserted1.022OBSOLETE. A mitotic cell cycle checkpoint that detects whether chromosome segregation is complete and negatively regulates cytokinesis following mitosis.GO:0000078trueobsolete cytokinesis after mitosis checkpointbiological_process26810052603780exactcell shape checkpoint268100526810052603780exact26809632603780exactcell morphogenesis checkpoint268096326809632603780exact260378026374162646000GOCprdef2829111GOCgo_curatorsdef2828596OntologyLoader1.02017-03-09T16:31:20+01:00http://www.goontology.org/2017-03-09T16:30:51+01:00rootGO Ontolgy2017-03-09T00:00:00+01:00Inserted1.022Any process that modulates the frequency, rate or extent of cyclin-dependent protein serine/threonine kinase activity.GO:0000079falseregulation of cyclin-dependent protein serine/threonine kinase activitybiological_process27451732603781broadregulation of cyclin-dependent protein kinase activity274517327451732603781broad27428392603781exactregulation of CDK activity274283927428392603781exact260378126319912632002part_ofgocheck_do_not_annotateTerm not to be used for d2603699ReactomeREACT_83686G1 Phase, Danio rerioxref_analog2816794ReactomeREACT_78665G1 Phase, Gallus gallusxref_analog2813992ReactomeREACT_93574G1 Phase, Xenopus tropicalisxref_analog2822216ReactomeREACT_78866G1 Phase, Sus scrofaxref_analog2814094ReactomeREACT_1590G1 Phase, Homo sapiensxref_analog2807631ReactomeREACT_34060G1 Phase, Canis familiarisxref_analog2811916ReactomeREACT_29795G1 Phase, Taeniopygia guttataxref_analog2809741ReactomeREACT_93384G1 Phase, Rattus norvegicusxref_analog2822115ReactomeREACT_101162G1 Phase, Bos taurusxref_analog2798886GOCmtg_cell_cycledef2828967ReactomeREACT_91654G1 Phase, Mus musculusxref_analog2821189Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase (i.e mitotic DNA replication for mitotic S-phase). To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during).OntologyLoader1.02017-03-09T16:31:20+01:00http://www.goontology.org/2017-03-09T16:30:51+01:00rootGO Ontolgy2017-03-09T00:00:00+01:00Inserted1.022The cell cycle 'gap' phase which is the interval between the completion of DNA segregation by mitosis and the beginning of DNA synthesis.GO:0000080falsemitotic G1 phasebiological_process26589882603782exactG1 phase of mitotic cell cycle265898826589882603782exact260378226268772626946ReactomeREACT_28713G1/S Transition, Xenopus tropicalisxref_analog2809194ReactomeREACT_88046G1/S Transition, Bos taurusxref_analog2819179ReactomeREACT_1783G1/S Transition, Homo sapiensxref_analog2807785ReactomeREACT_85355G1/S Transition, Sus scrofaxref_analog2817705ReactomeREACT_102687G1/S Transition, Arabidopsis thalianaxref_analog2799725ReactomeREACT_104577G1/S Transition, Saccharomyces cerevisiaexref_analog2800738ReactomeREACT_101799G1/S Transition, Taeniopygia guttataxref_analog2799235ReactomeREACT_107492G1/S Transition, Dictyostelium discoideumxref_analog2802339ReactomeREACT_109784G1/S Transition, Oryza sativaxref_analog2803587ReactomeREACT_104529G1/S Transition, Schizosaccharomyces pombexref_analog2800710GOCmtg_cell_cycledef2828967ReactomeREACT_106054G1/S Transition, Mus musculusxref_analog2801540ReactomeREACT_87037G1/S Transition, Drosophila melanogasterxref_analog2818619ReactomeREACT_110917G1/S Transition, Plasmodium falciparumxref_analog2804217ReactomeREACT_45711G1/S Transition, Caenorhabditis elegansxref_analog2812409ReactomeREACT_95294G1/S Transition, Rattus norvegicusxref_analog2823263ReactomeREACT_84226G1/S Transition, Gallus gallusxref_analog2817105ReactomeREACT_104020G1/S Transition, Canis familiarisxref_analog2800438ReactomeREACT_109821G1/S Transition, Danio rerioxref_analog2803606OntologyLoader1.02017-03-09T16:31:20+01:00http://www.goontology.org/2017-03-09T16:30:51+01:00rootGO Ontolgy2017-03-09T00:00:00+01:00Inserted1.022The mitotic cell cycle transition by which a cell in G1 commits to S phase. The process begins with the build up of G1 cyclin-dependent kinase (G1 CDK), resulting in the activation of transcription of G1 cyclins. The process ends with the positive feedback of the G1 cyclins on the G1 CDK which commits the cell to S phase, in which DNA replication is initiated.GO:0000082falseG1/S transition of mitotic cell cyclebiological_process2603783260877826450432603783part_ofGOCmtg_cell_cycledef2828967ReactomeREACT_683G1/S-Specific Transcription, Homo sapiensxref_analog2812833OntologyLoader1.02017-03-09T16:31:20+01:00http://www.goontology.org/2017-03-09T16:30:51+01:00rootGO Ontolgy2017-03-09T00:00:00+01:00Inserted1.022Any process that regulates transcription such that the target genes are involved in the transition between G1 and S phase of the mitotic cell cycle.GO:0000083falseregulation of transcription involved in G1/S transition of mitotic cell cyclebiological_process260378426319932632002part_ofgocheck_do_not_annotateTerm not to be used for d2603699ReactomeREACT_85811S Phase, Sus scrofaxref_analog2817930ReactomeREACT_92500S Phase, Mus musculusxref_analog2821642ReactomeREACT_97603S Phase, Danio rerioxref_analog2824554ReactomeREACT_108550S Phase, Rattus norvegicusxref_analog2802927ReactomeREACT_899S Phase, Homo sapiensxref_analog2820206ReactomeREACT_99645S Phase, Bos taurusxref_analog2825709ReactomeREACT_32013S Phase, Mycobacterium tuberculosisxref_analog2810848ReactomeREACT_96081S Phase, Dictyostelium discoideumxref_analog2823713ReactomeREACT_34043S Phase, Oryza sativaxref_analog2811905ReactomeREACT_110039S Phase, Schizosaccharomyces pombexref_analog2803718GOCmtg_cell_cycledef2828967ReactomeREACT_78845S Phase, Xenopus tropicalisxref_analog2814084ReactomeREACT_28988S Phase, Taeniopygia guttataxref_analog2809338ReactomeREACT_92759S Phase, Canis familiarisxref_analog2821786ReactomeREACT_81914S Phase, Saccharomyces cerevisiaexref_analog2815801ReactomeREACT_78838S Phase, Plasmodium falciparumxref_analog2814079ReactomeREACT_89318S Phase, Drosophila melanogasterxref_analog2819862ReactomeREACT_105829S Phase, Caenorhabditis elegansxref_analog2801428ReactomeREACT_82813S Phase, Arabidopsis thalianaxref_analog2816309ReactomeREACT_95174S Phase, Gallus gallusxref_analog2823188Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase (i.e mitotic DNA replication for mitotic S-phase). To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during).OntologyLoader1.02017-03-09T16:31:20+01:00http://www.goontology.org/2017-03-09T16:30:51+01:00rootGO Ontolgy2017-03-09T00:00:00+01:00Inserted1.022The cell cycle phase, following G1, during which DNA synthesis takes place as part of a mitotic cell cycle.GO:0000084falsemitotic S phasebiological_process26658332603785exactS phase of mitotic cell cycle266583326658332603785exact26662022603785exactS-phase of mitotic cell cycle266620226662022603785exact260378526319922632002part_ofgocheck_do_not_annotateTerm not to be used for d2603699ReactomeREACT_105223G2 Phase, Mus musculusxref_analog2801098ReactomeREACT_106415G2 Phase, Xenopus tropicalisxref_analog2801738ReactomeREACT_105307G2 Phase, Canis familiarisxref_analog2801151ReactomeREACT_85928G2 Phase, Sus scrofaxref_analog2817996ReactomeREACT_1915G2 Phase, Homo sapiensxref_analog2807901ReactomeREACT_96332G2 Phase, Danio rerioxref_analog2823859GOCmtg_cell_cycledef2828967ReactomeREACT_106836G2 Phase, Bos taurusxref_analog2801975ReactomeREACT_28975G2 Phase, Rattus norvegicusxref_analog2809332Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase (i.e mitotic DNA replication for mitotic S-phase). To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during).OntologyLoader1.02017-03-09T16:31:20+01:00http://www.goontology.org/2017-03-09T16:30:51+01:00rootGO Ontolgy2017-03-09T00:00:00+01:00Inserted1.022The cell cycle 'gap' phase which is the interval between the completion of DNA synthesis and the beginning of DNA segregation by mitosis.GO:0000085falsemitotic G2 phasebiological_process26590142603786exactG2 phase of mitotic cell cycle265901426590142603786exact2603786262687726269422603965part_ofReactomeREACT_103766G2/M Transition, Schizosaccharomyces pombexref_analog2800297ReactomeREACT_114616G2/M Transition, Arabidopsis thalianaxref_analog2805865ReactomeREACT_2203G2/M Transition, Homo sapiensxref_analog2808297ReactomeREACT_88369G2/M Transition, Rattus norvegicusxref_analog2819368ReactomeREACT_34062G2/M Transition, Mus musculusxref_analog2811917ReactomeREACT_87230G2/M Transition, Canis familiarisxref_analog2818721ReactomeREACT_83880G2/M Transition, Drosophila melanogasterxref_analog2816897GOCmtg_cell_cycledef2828967ReactomeREACT_87807G2/M Transition, Dictyostelium discoideumxref_analog2819045ReactomeREACT_107882G2/M Transition, Sus scrofaxref_analog2802554ReactomeREACT_87036G2/M Transition, Saccharomyces cerevisiaexref_analog2818618ReactomeREACT_92702G2/M Transition, Bos taurusxref_analog2821754ReactomeREACT_88018G2/M Transition, Caenorhabditis elegansxref_analog2819160ReactomeREACT_100942G2/M Transition, Danio rerioxref_analog2798750ReactomeREACT_28929G2/M Transition, Xenopus tropicalisxref_analog2809309ReactomeREACT_77778G2/M Transition, Taeniopygia guttataxref_analog2813523ReactomeREACT_30388G2/M Transition, Gallus gallusxref_analog2810004OntologyLoader1.02017-03-09T16:31:20+01:00http://www.goontology.org/2017-03-09T16:30:51+01:00rootGO Ontolgy2017-03-09T00:00:00+01:00Inserted1.022The mitotic cell cycle transition by which a cell in G2 commits to M phase. The process begins when the kinase activity of M cyclin/CDK complex reaches a threshold high enough for the cell cycle to proceed. This is accomplished by activating a positive feedback loop that results in the accumulation of unphosphorylated and active M cyclin/CDK complex.GO:0000086falseG2/M transition of mitotic cell cyclebiological_process27205162603787exactmitotic G2/M transition272051627205162603787exact260378726039662640744gocheck_do_not_annotateTerm not to be used for d2603699ReactomeREACT_82055M Phase, Rattus norvegicusxref_analog2815883ReactomeREACT_92998M Phase, Danio rerioxref_analog2821903ReactomeREACT_29488M Phase, Canis familiarisxref_analog2809583ReactomeREACT_88263M Phase, Xenopus tropicalisxref_analog2819309ReactomeREACT_109059M Phase, Saccharomyces cerevisiaexref_analog2803213ReactomeREACT_107095M Phase, Dictyostelium discoideumxref_analog2802115ReactomeREACT_910M Phase, Homo sapiensxref_analog2820832ReactomeREACT_87132M Phase, Bos taurusxref_analog2818663GOCmtg_cell_cycledef2828967ReactomeREACT_33490M Phase, Caenorhabditis elegansxref_analog2811621ReactomeREACT_93566M Phase, Gallus gallusxref_analog2822212ReactomeREACT_93131M Phase, Schizosaccharomyces pombexref_analog2821979ReactomeREACT_93720M Phase, Drosophila melanogasterxref_analog2822300ReactomeREACT_94536M Phase, Taeniopygia guttataxref_analog2822802ReactomeREACT_105412M Phase, Mus musculusxref_analog2801205Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase (i.e mitotic DNA replication for mitotic S-phase). To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during).OntologyLoader1.02017-03-09T16:31:20+01:00http://www.goontology.org/2017-03-09T16:30:51+01:00rootGO Ontolgy2017-03-09T00:00:00+01:00Inserted1.022A cell cycle phase during which nuclear division occurs, and which is comprises the phases: prophase, metaphase, anaphase and telophase and occurs as part of a mitotic cell cycle.GO:0000087falsemitotic M phasebiological_process26621962603788exactM phase of mitotic cell cycle266219626621962603788exact26622142603788exactM-phase of mitotic cell cycle266221426622142603788exact260378826319972603788part_ofgocheck_do_not_annotateTerm not to be used for d2603699ReactomeREACT_100605Mitotic Prophase, Saccharomyces cerevisiaexref_analog2798542ReactomeREACT_80300Mitotic Prophase, Gallus gallusxref_analog2814895ReactomeREACT_90347Mitotic Prophase, Canis familiarisxref_analog2820460ReactomeREACT_28443Mitotic Prophase, Taeniopygia guttataxref_analog2809059ReactomeREACT_83888Mitotic Prophase, Dictyostelium discoideumxref_analog2816902GOCmtg_cell_cycledef2828967ReactomeREACT_106058Mitotic Prophase, Drosophila melanogasterxref_analog2801543ReactomeREACT_765Mitotic Prophase, Homo sapiensxref_analog2813063ReactomeREACT_102122Mitotic Prophase, Mus musculusxref_analog2799416ReactomeREACT_79474Mitotic Prophase, Caenorhabditis elegansxref_analog2814424ReactomeREACT_90481Mitotic Prophase, Schizosaccharomyces pombexref_analog2820540ReactomeREACT_105127Mitotic Prophase, Danio rerioxref_analog2801042ReactomeREACT_28607Mitotic Prophase, Rattus norvegicusxref_analog2809138ReactomeREACT_32677Mitotic Prophase, Xenopus tropicalisxref_analog2811187Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase (i.e mitotic DNA replication for mitotic S-phase). To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during).OntologyLoader1.02017-03-09T16:31:20+01:00http://www.goontology.org/2017-03-09T16:30:51+01:00rootGO Ontolgy2017-03-09T00:00:00+01:00Inserted1.022The cell cycle phase which is the first stage of M phase of mitosis and during which chromosomes condense and the two daughter centrioles and their asters migrate toward the poles of the cell.GO:0000088falsemitotic prophasebiological_process260378926319962603788part_ofgocheck_do_not_annotateTerm not to be used for d2603699GOCmtg_cell_cycledef2828967ReactomeREACT_434Mitotic Metaphase, Homo sapiensxref_analog2812384Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase (i.e mitotic DNA replication for mitotic S-phase). To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during).OntologyLoader1.02017-03-09T16:31:20+01:00http://www.goontology.org/2017-03-09T16:30:51+01:00rootGO Ontolgy2017-03-09T00:00:00+01:00Inserted1.022The cell cycle phase, following prophase, during which chromosomes become aligned on the equatorial plate of the cell as part of a mitotic cell cycle.GO:0000089falsemitotic metaphasebiological_process260379026319952603788part_ofgocheck_do_not_annotateTerm not to be used for d2603699ReactomeREACT_1275Mitotic Anaphase, Homo sapiensxref_analog2807138GOCmtg_cell_cycledef2828967Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase (i.e mitotic DNA replication for mitotic S-phase). To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during).OntologyLoader1.02017-03-09T16:31:20+01:00http://www.goontology.org/2017-03-09T16:30:51+01:00rootGO Ontolgy2017-03-09T00:00:00+01:00Inserted1.022The cell cycle phase during which chromosomes separate and migrate towards the poles of the spindle the as part of a mitotic cell cycle.GO:0000090falsemitotic anaphasebiological_process26037912603791gocheck_do_not_annotateTerm not to be used for d2603699GOCmtg_cell_cycledef2828967Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase (i.e mitotic DNA replication for mitotic S-phase). To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during).OntologyLoader1.02017-03-09T16:31:20+01:00http://www.goontology.org/2017-03-09T16:30:51+01:00rootGO Ontolgy2017-03-09T00:00:00+01:00Inserted1.022The cell cycle phase during which the kinetochore microtubules shorten as chromosomes move toward the spindle poles as part of mitosis.GO:0000091falsemitotic anaphase Abiological_process26037922603791gocheck_do_not_annotateTerm not to be used for d2603699GOCmtg_cell_cycledef2828967Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase (i.e mitotic DNA replication for mitotic S-phase). To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during).OntologyLoader1.02017-03-09T16:31:20+01:00http://www.goontology.org/2017-03-09T16:30:51+01:00rootGO Ontolgy2017-03-09T00:00:00+01:00Inserted1.022The cell cycle phase during which the polar microtubules elongate and the two poles of the spindle move farther apart as part of mitosis.GO:0000092falsemitotic anaphase Bbiological_process260379326319992603788part_ofgocheck_do_not_annotateTerm not to be used for d2603699GOCmtg_cell_cycledef2828967Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase (i.e mitotic DNA replication for mitotic S-phase). To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during).OntologyLoader1.02017-03-09T16:31:20+01:00http://www.goontology.org/2017-03-09T16:30:51+01:00rootGO Ontolgy2017-03-09T00:00:00+01:00Inserted1.022The cell cycle phase which follows anaphase during M phase of mitosis and during which the chromosomes arrive at the poles of the cell and the division of the cytoplasm starts.GO:0000093falsemitotic telophasebiological_process2603794260432226043232604326GOCgo_curatorsdef2828596This term was made obsolete because it was not defined and the string name implied two separate processes.OntologyLoader1.02017-03-09T16:31:20+01:00http://www.goontology.org/2017-03-09T16:30:51+01:00rootGO Ontolgy2017-03-09T00:00:00+01:00Inserted1.022OBSOLETE (was not defined before being made obsolete).GO:0000094trueobsolete septin assembly and septum formationbiological_process27507092603795exactseptin assembly and septum formation275070927507092603795exact2603795GO:0015177263186926378592643702GOCaidef2828262OntologyLoader1.02017-03-09T16:31:20+01:00http://www.goontology.org/2017-03-09T16:30:51+01:00rootGO Ontolgy2017-03-09T00:00:00+01:00Inserted1.022Enables the transfer of S-adenosylmethionine from one side of a membrane to the other. S-adenosylmethionine is S-(5'-adenosyl)-L-methionine, an important intermediate in one-carbon metabolism.GO:0000095falseS-adenosyl-L-methionine transmembrane transporter activitymolecular_function26658682603796exactS-adenosyl methionine transporter activity266586826658682603796exact26661272603796exactS-adenosylmethionine permease activity266612726661272603796exact26658662603796exactS-adenosyl methionine permease activity266586626658662603796exact26661352603796broadS-adenosylmethionine transporter activity266613526661352603796broad26662782603796exactSAM transmembrane transporter activity266627826662782603796exact26661322603796exactS-adenosylmethionine transmembrane transporter activity266613226661322603796exact260379626089192609172gosubset_prokProkaryotic GO subset2603714ReactomeREACT_118184Sulfur amino acid metabolism, Canis familiarisxref_analog2806760ReactomeREACT_118256Sulfur amino acid metabolism, Staphylococcus aureus N315xref_analog2806793ReactomeREACT_118314Sulfur amino acid metabolism, Arabidopsis thalianaxref_analog2806825ReactomeREACT_118541Sulfur amino acid metabolism, Danio rerioxref_analog2806926ReactomeREACT_118323Sulfur amino acid metabolism, Xenopus tropicalisxref_analog2806829ReactomeREACT_118099Sulfur amino acid metabolism, Escherichia colixref_analog2806723ReactomeREACT_118094Sulfur amino acid metabolism, Bos taurusxref_analog2806720ReactomeREACT_118309Sulfur amino acid metabolism, Gallus gallusxref_analog2806822ReactomeREACT_118518Sulfur amino acid metabolism, Dictyostelium discoideumxref_analog2806918GOCaidef2828262ReactomeREACT_115639Sulfur amino acid metabolism, Homo sapiensxref_analog2806405ReactomeREACT_118370Sulfur amino acid metabolism, Mus musculusxref_analog2806853ReactomeREACT_118349Sulfur amino acid metabolism, Oryza sativaxref_analog2806842ReactomeREACT_118291Sulfur amino acid metabolism, Caenorhabditis elegansxref_analog2806809ReactomeREACT_118166Sulfur amino acid metabolism, Taeniopygia guttataxref_analog2806750ReactomeREACT_118227Sulfur amino acid metabolism, Mycobacterium tuberculosisxref_analog2806780ReactomeREACT_118084Sulfur amino acid metabolism, Rattus norvegicusxref_analog2806717ReactomeREACT_118203Sulfur amino acid metabolism, Sus scrofaxref_analog2806771ReactomeREACT_118463Sulfur amino acid metabolism, Schizosaccharomyces pombexref_analog2806899ReactomeREACT_118328Sulfur amino acid metabolism, Drosophila melanogasterxref_analog2806832ReactomeREACT_118388Sulfur amino acid metabolism, Saccharomyces cerevisiaexref_analog2806864ReactomeREACT_27187Sulfur amino acid metabolism, Mycobacterium tuberculosisxref_analog2808791OntologyLoader1.02017-03-09T16:31:20+01:00http://www.goontology.org/2017-03-09T16:30:51+01:00rootGO Ontolgy2017-03-09T00:00:00+01:00Inserted1.022The chemical reactions and pathways involving amino acids containing sulfur, comprising cysteine, homocysteine, methionine and selenocysteine.GO:0000096falsesulfur amino acid metabolic processbiological_process27540262603797exactsulphur amino acid metabolism275402627540262603797exact27540252603797exactsulphur amino acid metabolic process275402527540252603797exact27539312603797exactsulfur amino acid metabolism275393127539312603797exact2603797260379726105092626381gosubset_prokProkaryotic GO subset2603714GOCaidef2828262OntologyLoader1.02017-03-09T16:31:20+01:00http://www.goontology.org/2017-03-09T16:30:51+01:00rootGO Ontolgy2017-03-09T00:00:00+01:00Inserted1.022The chemical reactions and pathways resulting in the formation of amino acids containing sulfur, comprising cysteine, methionine and selenocysteine.GO:0000097falsesulfur amino acid biosynthetic processbiological_process27539262603798exactsulfur amino acid biosynthesis275392627539262603798exact27539252603798exactsulfur amino acid anabolism275392527539252603798exact27539322603798exactsulfur amino acid synthesis275393227539322603798exact27540222603798exactsulphur amino acid biosynthetic process275402227540222603798exact27539302603798exactsulfur amino acid formation275393027539302603798exact27540212603798exactsulphur amino acid biosynthesis275402127540212603798exact2603798260379726108902626382gosubset_prokProkaryotic GO subset2603714GOCaidef2828262ReactomeREACT_115654Degradation of cysteine and homocysteine, Homo sapiensxref_analog2806416OntologyLoader1.02017-03-09T16:31:20+01:00http://www.goontology.org/2017-03-09T16:30:51+01:00rootGO Ontolgy2017-03-09T00:00:00+01:00Inserted1.022The chemical reactions and pathways resulting in the breakdown of amino acids containing sulfur, comprising cysteine, methionine and selenocysteine.GO:0000098falsesulfur amino acid catabolic processbiological_process27539292603799exactsulfur amino acid degradation275392927539292603799exact27539282603799exactsulfur amino acid catabolism275392827539282603799exact27539272603799exactsulfur amino acid breakdown275392727539272603799exact27540242603799exactsulphur amino acid catabolism275402427540242603799exact27540232603799exactsulphur amino acid catabolic process275402327540232603799exact260379926131522643702gosubset_prokProkaryotic GO subset2603714GOCmtg_transportdef2828983ISBN0815340729def2775103GOCaidef2828262OntologyLoader1.02017-03-09T16:31:20+01:00http://www.goontology.org/2017-03-09T16:30:51+01:00rootGO Ontolgy2017-03-09T00:00:00+01:00Inserted1.022Enables the transfer of sulfur amino acids from one side of a membrane to the other. Sulphur amino acids contain sulfur in the form of cystine, methionine or their derivatives.GO:0000099falsesulfur amino acid transmembrane transporter activitymolecular_function27539332603800broadsulfur amino acid transporter activity275393327539332603800broad27540292603800broadsulphur amino acid transporter activity275402927540292603800broad27540272603800exactsulphur amino acid transmembrane transporter activity275402727540272603800exact2603800